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專題探索
預防勝於治療
一氧化氮與健康
一氧化氮—人體內無處不在
ɓःʷಢ
(Nitric Oxide, NO)
ٙʷኪʱɿό
މ
NO
d݊
ɓ၇ೌЍeೌঔंfɓःʷಢٙ̒সಂ
ܘ
fɽ
ंʕٙɓःʷಢ੬ԸІӛԓ҈ंձՉ̴ᐑྤϮ
ݑ
d
ܘ
ၾः೯͛ˀᏐd͛ϓɚःʷಢf
ɓःʷಢίɛlzd̙Ⴍ݊ೌஈʔίf̥
ࠅ
ϞА૰
Ց༺ٙή˙dఱϞ̴
ࡁ
ٙᔳᅂf̴ϞՇ
ࡈ
Ը๕dɓ
ࡈ
݊ԸІ
אڌ
ᙲɝٙೌዚಢ
(
νა͚
ذ
ձ౷
ඒഃ
)
ٙʷኪࠥ༆ၾᔷʷi̤ɓ
ࡈ
݊͟
L -
ၚऄა
(L-Arginine)
ɓःʷಢΥ㺛
(nitric oxide synthase,
NOS)
ළʷ୭ᯝਿ
ה
ପ͛fɛʕٙɓःʷಢΥ㺛Ϟ
ɧᗳdί͍੬ઋ
ر
ɨd̙πίlzͤe̮մग़ձ
ɽ໘ʕfίतࣿઋ
ر
ɨdɰ̙Ⴐኬପ͛d၈
މ
Ⴐ
ኬۨɓःʷಢΥ㺛f
一氧化氮是一種化學信使
ɛ
ߤ
ʝʘගd̙ᔟʷኪ
ڦ
Դʱɿෂ༟ৃd
ɓःʷಢЪ
މ
ɓ၇
ڦ
Դʱɿd̴̙˸߈൳၇
ߤ
ʘගdஷཀʱ
ؤ
ඎᄣಯٙሜືdෂ
ܘ
εᅂᚤԒ
͛ଣ
ݺ
ਗٙ༟ৃdᏍп੶ʷృᐑӻ୕eе
ޥ
ӻ୕ձ
ग़ӻ୕ٙ̌ঐdᅂᚤཁʿ٬eӿe
ߞ
e͛ಟኜഃ
ኜ֜dԷνjίlzͤʕପ͛ٙɓःʷಢdЪ
މ
ɓ၇
lzͤബੵΪᅰd˴
ࠅ
Ъ͜А၍d̙ԴՉബੵd˸
ᄣ̋А၍lzٙА
ݴ
ඎdԨᖢ֛АᏀiί̮մग़ձɽ
໘ʕପ͛ٙɓःʷಢd
ۆ
Ъ
މ
ഥɪ໗९ձᑔ˸̮
ٙग़ሯd࿁А၍eऎၧe
໑ߞ
༸ഃ̮մ፩̈
ग़ҵՓˀᏐପ͛Ъ͜iЇ͟ႰኬۨɓःʷಢΥ
㺛Υϓٙɓःʷಢd
ۆ
̙ஷཀ၇ࢰ࿁
ف
सeе
ޥ
ˀᏐe
ߤ
࡙ɳഃε၇षଣཀପ͛ᅂᚤf
一氧化氮與血管舒張
ɓःʷಢ࿁ɛ͛ଣ
ݺ
ਗٙᅂᚤd
ܘ
ࠠ
ࠅ
ٙɓ
ࡈ
˙
ࠦఱ̴݊ঐˏৎА၍ٙബੵf
ɓःʷಢ
ޟމ
ჿঐˏৎА၍ബੵkɓःʷಢ݊͟А
၍lzͤ
ߤ
ᙑ׳̈Ըٙfᙑ׳̈Ըٙɓःʷಢɓ
ၾА
९ߎ
ʕٙ㹷აᐑʷ㺛ഐΥd༈㺛у઼ਗd
ഐ
؈
Դɧᐟა㹷ᔷʷϓᐑᐟა㹷
(cGMP)
dᐑᐟ
ა㹷Ύ઼ਗᏐٙஐͣዧ㺛dԴ
ߤ
ᆉlzඑᕎɿ
Σ
ߤ
̮
ݴ
ਗd
ߧ
Դ
ߤ
ᆉlz༷ᕎඑᕎɿዢ
ܓ
ࠥЭdԴ
А၍̻Єബੵf
А၍̻ЄബੵdϞлА૰ٙ
ݴ
ਗdԴΌԒА၍
˸ஷdःձᐄቮ
ي
ሯ๕๕ʔᓙٙΣኜ֜፩d
Νࣛ
ߤ
ٙ˾ᑽପ
ي
˸ʿࣛ༶Ԑfɓःʷಢஷཀ
ബੵА၍ٙЪ͜ၾኜ֜ٙ
ݺ
ਗ೯͛ʲٙᑌᖩj
ஷཀᓒੵ٬А၍d࿁٬ృᐑৎሜືЪ͜fіɝЭዢ
ܓ
ɓःʷಢd̙ࠥЭࡡ೯٬ਗএ৷Ꮐe˂ː
ɓःʷಢ݊
ޟ
䟕kԨ
ڢ
ɛɛே
ء
จՑdШᖹ
ي
ਃࡩdᛓႭཀٙɛࢵఱʔˇf
ۍ
ࡡԸdਃࡩٙᖹଣЪ
͜ձɓःʷಢϞഹʲٙᗫ
ڷ
f
ܣ
䟕ึճkɓःʷಢʔ݊ɽंʕϞٙϮ
يݑ
k̴౷ཁπίӛԓ҈
ंeіeձչѫዷደ
ي
ʕd
ܣ
ჿɓɨɿఱᜊϓɓ၇ᖹ
ي
ճkӚ፹dу
ک
ίɛlzdɓःʷಢཀεd࿁ੰ
ɰ݊ʔлٙfШቇඎٙɓःʷಢd
ۍ
݊ੰ
ה
̀ცfɛlzɓःʷಢ͛ϓٙεˇձሜື݊щ̻ፅdձ
ܘ
εश
षνːА၍षe໑
ߞ
षe٬षeӿषeᐖसഃٙ೯͛ձ೯࢝ேภɪᗫ
ڷ
fӺᒔ
ڌ
,
ɓःʷಢί
ط
ᐕː
А၍शषʕՈϞᜑٙЪ͜f
࿁ɓःʷಢٙவԬอႩᗆdྼϞ፠㠗ε߅ኪٙрɢdˈՉ݊͟Ԣᅃ
ጒ
ז
ᅃeᖯЬत
F.
Н۰ࡩतձ
༩ɻ
J.
ͺࣸॶᖯɧЗ߅ኪٙᅆdԴவ
ࡈ
ϲࢅɓᚔϾϓ
މ
˾ٙʱɿlϾ˼
ࡁ
ɧЗ্ٙ
ᘠɰΪϾՑ
ٵ
֛dΝࣛᐏ
1998
ϋፕԎဧ͛ଣʿᔼኪᆤfᑊᚤৎཀ
ܝ
dɤϋཀ̘ədɛ
ࡁ
࿁ɓःʷಢ
ɦϞəһεٙႩᗆf݂ίϤආБɓԬࣰଣձઞ॰dЪ
މ
࿁ɓःʷಢٝᗆٙ౷ʿf
簡志瀚 Kan Chi Hon