保健 - 第104期 - page 53

專題探索
53
IL-17
ف
सˀᏐ
IL-17
݊ͦ
ۃ
อ೯ତٙ˴
͟াኳ
T
ߤ
ʱ
ؤ
ٙɓ၇
فڮ
׌୚
ߤ
ΪɿfՈϞ੶ɽ
ם
෍ʕ׌୐୚
ߤ
ٙঐɢe
ɦঐ
ڮ
ආε၇୚
ߤ
ᙑ׳
ف
׌Ϊɿf˴
ܼ̍
IL-1
e
IL-6
e
IL-8
e
IL-23
e
TNF
ձ
IFN-r
ഃf݊ɓᗳอۨͣ
ʧ९d࿁
ف
सٙ೯͛೯࢝ৎഹʔׁ̙ൖٙЪ͜f
߅ኪ࢕੽ʃཽٙ
T
ߤ
૸ˋᆯ୚
ߤ
ʕ࠯΋೯ତə
IL-
17A
dԨ೯ତίਿΪଡ଼ʕᒔўϞՉ˼ʞ
ձ
IL-17A
Ν
๕ٙਿΪd͟Ϥdɛ
ਗ਼ʬ
Ν๕ٙ୚
ߤ
Ϊɿᓥɝ
ɓ
อٙ
IL-17
࢕ૄdʱйնΤ
މ
IL-17A
Ց
IL-17F
f
ΝࣛdᒔҬՑ̴
ٙա᜗࢕ૄfவԬʔΝٙ
IL-17
̙
˸ഐΥ޴࿁Ꮠٙա᜗d੽ϾʧኬʔΝٙ
ف
सˀᏐf
Ցͦ
೯ۃ
ତՉၾዚ᜗ε၇शष޴ᗫfतй݊ၾ٬௅
ݑ
eࡲఁeᗳࠬ᐀׌ᗫື
ف
eኜ֜୅ಔe໑༸
ف
सഃ
ف
स׌शषϞᗫf
IL-10
ၾ໕ᆯ
IL-10
݊ɓ၇˴
ࣖ͟Ꮠ
T
ߤ
ପ͛ٙе
ޥ
ሜືΪɿd
݊ՈϞе
ޥ
ҵՓЪٙ͜Ҥ
ف
ʱɿf
ڐ
ϋԸٙ޼Ӻ೯
IL-10
࿁໕ᆯ̙ঐ೯౨ᕐΣٙе
ޥ
ሜືЪ͜fу݅
̙
ڮ
ආ໕ᆯ͛
ڗ
dɦ̙ҵՓ໕ᆯ೯͛೯࢝ձᔷ୅f
IL-10
ڮ
ආ໕ᆯ͛
ڗ
݊Ϊ
މ
I/
ٜટҵՓࣖᏐ
T
ߤ
ಟձቋ୅ঐɢԨɨሜ޴ᗫΪɿٙପ͛f
2/
ஷཀҵՓҤ
ࡡ౤я୚
ߤ
ٙ
ݺ
ʷЪ͜dପ͛࿁
T
ߤ
ٙҵՓࣖᏐԸ
Җϓе
ޥ
ҵՓᐑྤd੽ϾႰኬ໕ᆯе
ޥ
৚අf
ה
˸d
IL-10
˥̻౤৷ࣛd
T
ߤ
࿁໕ᆯ୚
ߤ
ٙ૨ෆࣖᏐ׼
ᜑ஗ҵՓf
IL-10
ɦঐԴ໕ᆯҵՓ݊Ϊ
މ
̴ঐ
1/
̙˸ҵՓ
TH17
ߤ
e̶አ୚
ߤ
ʿ
IL-23
ڮ
ආ໕ᆯ೯͛೯࢝ٙ
ف
׌Ϊ
ɿdආϾҵՓ໕ᆯ޴ᗫ
ف
सd౤৷ዚ᜗Ҥ໕ᆯЪ͜i
2/
̙˸ٜટ
א
ගટ
ݺ
ʷ
NK
ߤ
ձ໕ᆯत៦׌
CD8+T
ߤ
Ԩ౤৷Չ
ݺ
׌d੽Ͼ౤৷ዚ᜗࿁໕ᆯٙ૨ෆࣖ
ᏐdҵՓ໕ᆯٙ೯࢝ձᔷ୅f
IL-10
வ၇࿁໕ᆯᕐΣሜືٙԈ༆dᒱ್ʥπί஢ε
̙ઞীʘஈdШ࿁̴ٙଉɝ޼Ӻ
,
ᒔ݊
ܘ
Ϟྼყจ່
ձഗɛ˸䖭೯ٙf
IL-1
ၾҵᝨस
дඤձ
༺ڌ
ѩʊϓ̌fኽ
2010
ϋ
ܓ
Ң਷̈
و
ٙе
ޥ
઺߅ࣣ
༱ה
dజ༸ٙͣʧ९ʊϞ੽
IL-1
Ց
IL-33
ɧɤɧ၇fͣʧ९၇ᗳ
ܘ
ε˲̌ঐ΢ମfତසఱɓԬ
ˢ༰ࠠ
ٙd
א
อ೯ତٙd
א
࿁ᑗґᗫ
༰ڷ
੗ʲٙͣ
ʧ९dᔊʧνɨf
IL-2
I L - 2
dɦ၈
މ
T
ߤ
͛
ڗ
Ϊɿ
( T c e l l g r o w t h
factor,TCGF)
CD4 Th1
ପ͛d
CD8 T
ߤ
ɰପ͛
ˇඎ
IL-2
f݊ˏৎ
T
ߤ
ᄣಟٙ˴
ٙe௰ࠠ
ٙ୚
ߤ
Ϊɿf
IL-2
ஷཀၾ
T
ڌߤ
ࠦٙ
IL-2
ա᜗ٙतମഐ
ўϾ
ڮ
Դ
T
ݺߤ
ʷdԨආɝʱ൓ً࿒fϤ̮d
IL-2
ᒔ̙Րዧ
NK
ߤ
ٙ͛
ڗ
ձᄣ੶Չ૨ෆ̌ঐdԨዧ೯
B
ߤ
͛
ڗ
ձҤ᜗ٙପ͛f
IL-12
IL-12
Ъٙ͜ཪ୚
ߤ
˴
݊
T
ߤ
ձ
NK
ߤ
f݊ஹટ
˂್е
ޥ
ձᐏ੻׌е
ޥ
ٙɓ
ॲ੭fঐϞࣖή౤
৷ዚ᜗ٙ୚
ߤ
е
ޥ
̌ঐf͛
ي
ኪ̌ঐܼ̍ᄣ੶
NK
ߤ
ձ
T
ߤ
ٙ૨ෆঐɢf
IL-18
IL-18
ڐ
ϋԸอ೯ତٙ୚
ߤ
Ϊɿdഐ࿴ၾ
ߤ
lz
ڦ
໮ᔷኬஷ༩ၾ
IL-1
޴Чďঐၾ
IL-12
޴ЧdՈҤ໕
ᆯeҤช
ݑ
ٙ͛
ݺي
׌f
IL-4
d
IL-5
ၾཀઽˀᏐ
IL-4
݊͟
Th2
ߤ
ପ͛fՉ͛ଣ̌ঐ݊ሜື
IgE
ձ٭ɽ
אߤ
ෘა׌୐୚
ߤ
ʧኬٙе
ޥ
Ꮠഈf݊٭ɽ୚
ߤ
ٙ
͛
ڗ
Ϊɿϊၾ
IL-3
՘ΝЪ͜dՐዧ٭ɽ୚
ߤ
ᄣಟf
IL-5
͟
Th2
ߤ
ձዧ
ݺ
ٙ٭ɽ୚
ߤ
ପ͛f˴
̌ঐ݊
Րዧෘა୐୚
ߤ
͛
ڗ
ձʱʷdዧ
ݺ
ϓᆞෘა୐୚
ߤ
d
ᄣ੶Չ૨ෆ੔͛ᔥٙঐɢfίᙀᔥช
ݑ
ࣛձཀઽˀ
Ꮠ׌शषࣛٙෘა׌୐୚ᄣε˴
݊͟
IL-5
ˏৎٙf
IL-5
ձ
IL-4
ٙ̌ঐ޴ʝ໾̂d
ڮ
Th2
ߤ
ʧኬٙཀ
ઽˀᏐfձ
IL-2
e
IL-4
՘Νdᄣ੶ϓᆞ
B
ߤ
Υϓ
Ig
d
तй݊
IgA
f
ཀઽˀᏐఱ݊
Th2
ݺߤ
׌ཀ৷d˸Їˏৎе
ޥ
̻ፅ
̰ሜf
ط
ᐕཀઽ੬ٙ͜ಯઽᐕ
ج
d̙Դ
Th2
࿁ཀઽࡡ
ପ͛
ߗ
ա׌dಯˇ
IL-4
ٙପ͛f
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