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防病之窗
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ಯˇᖹ๕शषٙ೯͛f
Drug-induced Disorders: Mind the Progressive Annual Increases
Drug-induced disorders, especially among the elderly, are getting commoner these days. As with suboptimal immunity, the elderly may
have multiple diseases, at times concomitantly; with their long list of drugs, the elderly is specially prone to drug-induced disorders,
e.g,, streptomycin and gentamycin induce toxic deafness; bleomycin, interstitial pneumonitis (chemical pneumonia), broad spectrum
antibiotics, “pseudomembranous colitis,” a severe inflammation of the colon; the anti-hypertensive hydralazine, lupus (SLE, an auto-
immune disorder). Relevant factors in the elderly are: (1) Poor absorption of the drugs (2) Poor metabolism of drugs (3) Delayed
excretion of drugs (4) Uneven distribution of drugs in the body. Thus, the elderly should take these steps for prevention: (1) All drugs
taken must be prescribed by your doctor (2) If feasible, manage osteoporosis, muscle aches, poor appetite, insomnia, etc., without
drugs (3) As obesity, atherosclerosis, hypertension, coronaries and diabetes, etc., are all closely related, an integral approach is
preferred (4) Use oral medications whenever feasible (5) If feasible, dietary control is preferred to drugs. All these together go a long
way to prevent drug-induced disorders!