保健 - 第88期 - page 56
54
၇
אيݭ
ᖹ
ي
ٙʕ
ݭ
f͵̙Ԉ׳࢛ᇞ࢛ٙe
ഽ
९ݭ
ிϓٙ
ߤ
ฦෆfᒔϞఱ݊ିᶶ९ഃᇞ
խі㺛ॹ˶ˏ
ߧ
͛
ي
ःʷཀٙღᖟf
缺氧與疾病
࿔ॹःၾशषٙᗫ
ڷ
d˚ूաՑɛ
ࡁ
ٙࠠൖd
ޟ
ЇϞɛႩ
މ
d¨ॹः݊ɓʲ࿔षٙ࣬๕f©ᑘɭ
ᐖसeϼϋᖝьഃٙ೯͛
೯א
࢝ேၾॹःҰɪᗫ
ڷ
d
࠽
ᗫ
ء
ձઞ॰f
ॹःၾᐖसᓒ
2012
ϋ
5
˜
3
˚
ߕ
ӊ˚߅ኪၣ१జ༸d࣬ኽР
ط
ԭ
ɽኪٙ௰อӺϓ
၈؈
d
ߤ
ॹः̙ঐ݊
ݔ
Ԭᐖस
Ҟᓒٙ˴
ࠅ
࣬๕fӺίɖᗳᐖसjԪ໗ᐖe
ഥᐖeӿᐖe٬ᐖeф੫ᐖeঈ໗ᐖձ
ߞ
ᐖʕdѩ
೯ତᐖ
ߤ
lzٙўःඎɨࠥfԨႩ
މ
dўःඎࠥ
ՑЭ
ܓ
ࣛdක
ڗ
̈อА၍dϾ৷
ߤ
ٙ
ўःdᅲࣛಯᇠəᐖसٙ೯࢝dШՉ
ܝ
Ϊᐖ
ߤ
ඎ
ᄣɽdһ̋ॹःٙઋ
ر
̈ତdҖϓəెృᐑdᐖ
ߤ
༹˸ᓒf
ၽᝄኪ٫͵൛dᐖ
൳ڗ൳ߤ
ɽd
ఱึ̈ତॹःdᐖ
މߤ
əᐏ՟ः
ंdఱึᔷՑՉ̴͍੬ٙኜ֜
̘fԨ
ܓ
ҬՑᐖ
ߤ
ᔷٙ
ݑ
Ѝሯᅺা
HDAC3
ʿ
WDR5
f˼
ࡁ
ᒔ೯ତdᐖ
ߤ
ॹःࣛd̙
Ⴐ೯
HIF-l
ƹਿΪdϾ
ݺ
ʷᔷ
ਿΪ
TWIST
ձ
Snail
dԴᐖ
ߤ
˸ᔷf
ॹःၾϼϋᖝьस
ڛ
ဧভऎᎰष
(AD
dϼϋᖝьस
)
ٙ೯
षዚՓЇʦ͊dϞ၇ʔΝኪႭfΪϤd
Їʦ֠ॹ˶Ϟࣖٙ
ط
ᐕ˓
ݬ
fШί೯षཀʕd̙
˸̈ၾ࿔ॹःً࿒ʲᗫf
1.
ॹःၾƺዠ४ᅵ㹻
(
ƺ
-Amyloidpeptide
d
A
ƺ
)
ٙ͛
ϓϞᗫf
A
ƺႰኬ
ݺ
ःᗳ
ي
ሯٙପ͛dˏ
ߧ
ग़
ʩ࡙ɳd
ڮ
ආ
AD
ٙषଣᜊʷf
2.
͟ग़ʩ༰Չ̴ଡ଼ᔌ
ߤ
dஈһ৷ٙ
ݺ
ः
л͜dഐΥःίА૰lzɰ̀ᔷᜊ
މ
༷ᕎः
ܝ
ʑঐ
ᘝՑଡ଼ᔌʕd
הߤ
л͜f
缺氧的發生
ɪ
ࠑ
¨ःආɝ
ߤ
ٙ
ݴ
˥ᇞ©̙˸̈d̮
ޢ
ःіɝ٬
ظ
eᘝɝА૰dΎၾА
ߎ
ஐͣഐΥd
͟А૰ృᐑ፩ՑΌԒd௰
ܝ
ଡ଼ᔌ
ߤ
ᙲ՟л
͜fவ̬
ࡈ
ᐑືdᐑᐑϔdၡஹd̈ʔ̒
ᓃࢨ፹dщ
ۆ
d̥
ࠅ
Չʕɓᐑື̈ତॎၛࣛdே
ึԴ
ߤ
ʔՑ̂ԑٙःd
א
ʔঐ̂ʱл͜ःd
ϤࣛԒఱ
೯ࠅ
͛ɓӻΐٙषଣᜊʷd၈
މ
ॹः
(hypoxia)
fॹः೯͛ٙࡡΪϞɨ̬ࠦ၇j
іɝ٬
ظ
ٙःʔԑ
іɝ٬
ظ
ٙःʔԑeᘝɝА૰ٙ
ܓ
ಯ࿔eᘝ
ඎಯˇd੬Ԉஈ৷ࡡe৷٤
א
ஷࠬʔԄஈfɦ
א
ίխі༸द॥
ڜא
෦e
٬א
शषࣛfԒ
މ
ə࿁ॹःٙ˾Ꮅd̙̈ତխі̋ଉ̋Ҟdஷंඎᄣ
̋fͤᇮࣛԈ
ڡ
ഓf߰˾Ꮅʔԑd̙ˏৎ
ܢ
٬˥
໕dᘌࠠࣛึ̈ତխіҵՓf
А
ߎ
ஐͣҷᜊ
А
ߎ
ஐͣᅰඎʔԑ
א
ሯҷᜊd
੬Ԉ၇மА
א
ɓःʷ၁ʕ
ݭ
fமАࣛА
ߎ
ஐͣᙳःཀ
ˇfɓःʷ၁ʕ
ݭ
ࣛdः
ɓःʷ၁ᘩ
ن
՟˾ၾА
ߎ
ஐͣഐΥfःΣଡ଼ᔌᘝٙ
ܓ
ಯ࿔fமАࣛषɛͤᇮ
ႏͣfɓःʷ၁ʕ
ݭ
dͤᇮя
ᙶࣹ
ߎ
Ѝf
Аృᐑღᖟ
ΌԒА૰ృᐑღᖟdଡ଼ᔌА
ݴ
ඎಯˇf
੬Ԉːɢস။ʿ;дഃࣛf;дઃ٫ː፩̈ඎಯ
ˇʿΌԒॹःᘌࠠdଢ଼ʿࠠ
ࠅ
ኜ֜f҅ృᐑ
ღᖟdԈএ၍
ف
eਗএഎᅵʷeАࣼҖϓʿࣼ
෦dːЄʿ໘෦੬Κʿ͛նf
ߤ
л͜ःମ੬
ଡ଼ᔌ
ߤ
л͜ःମ੬dԈ↾ʷ
ي
eିʷ૫eᐟഃ
預防勝於治療
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