保健 - 第92期 - page 8
8
癌症探秘
抗癌之戰目標在哪裡?
1939
ϋ
9
˜dᅃԓකආ
ت
ᚆdୋɚϣ˰
ޢ
ɽක
əfϤࣛࣨᜊவɓอ൚̥Ϟ
8
ࡈ
˜ٙ͛նf
ي
ଣ
ኪ
ޚ
ဧίఐ
ط
ശସɽኪٙɓϣଣሞ
ي
ଣኪஔึ
ᙄɪϣ೯бə˼ٙவɓ೯ତfɧϋ˸
ܝ
dਿࣨ
ᜊࡡଣක೯ࡡɿᅁٙਟ۞
ࠇ
ྌක༶Бfɦཀ
əɧϋd
1945
ϋ
8
˜
6
˚dɓᒶΤ
މ
ʃӲ܀ٙࡡɿᅁ
ί˚͉ᄿࢥɪ٤ᖑ
ގ
f
ߕ
ঘ٤ঘ˂҅݊
1958
ϋ
10
˜
1
˚ϓͭٙf
11
ϋ
˸
ܝ
dՇЗ
ߕ
ɛ೮ɪ˜ଢfᖭႡɛᗳਿΪྡᗅ
ٙӺɰఱආБə
18
ϋd௰Ϙ݊߅ኪ
ࡁ
ί̋ψ
SantaCruz
̜කٙɓϣʃۨኪஔึᙄɪ̈வɓซ
ج
ٙfఱၑ݊๑Ց
Watson
ၾ
Crick
ॎ༆
DNA
ഐٙϋ
˾dɰఱ݊̒
ࡈ
˰
ߏ
f
ԫᐖसӺٙ߅ɛࡰʔᗴจਂவᅵٙˢ༰f
εᐖसӺɛࡰႩ
މ
dᐖसӺʔΝਟ۞
ࠇ
ྌe˦ᇋ߅ኪ
ޟ
Ї፲ෂኪӺd
ܘ
ᗭ
މ
ண֛ͦᅺf
̙˸
ٵ
֛ٙ݊dᐖसٙܿΝɪ
ࠑ
ԟԬɽ߅ኪ
ࠇ
ྌҁΌ
ʔΝfࡡΪ݊ᐖस૨˓˄ኸ
ڗ
ᜊʷəf൬ਔ݊;
M.D.Anderson
ᐖसʕːᐖ͛
ي
ኪٙ˴d˼ܸ̈jᐖ
ߤ
ٙतᓃఱ݊Չ፲ෂኪʔᖢ֛fᐖ
ߤ
ٙ
DNA
ʔΝ
͍੬
ߤ
ٙ
DNA
d͍੬
ߤ
ʱࣛdՉ፲ෂ
ڦ
ࢹҁ
ߕ
ೌॹήልႡՑɨɓ˾
ߤ
iϾᐖ
ߤ
ʱࣛdልႡՑ
ܝ
˾ٙ፲ෂ
ڦ
ࢹ
ۍ
ึҷᜊdϾ˲፲ෂ
ڦ
ࢹٙฆᜊʷึ
ኬ
ߧ
ᐖ
ߤ
Б
މ
ٙᜑഹᜊʷfഐ
؈
ఱ݊ɛ
ࡁ
Ⴉ
၇ݔމ
ᐖ
ߤ
݊Νɓ၇
ߤ
ٙࣛ
ࡉ
dྼყɪவ၇ᐖ
ߤ
ʊʱ
ʷ̈ᗭ˸
ࠇ
ᅰٙʔΝ
ߤ
dϓɓ
ࡈ
ᐖ
ߤ
ɽૄdவ
Ԭᐖ
ߤ
Ϟٙतᓃd༓ൟೌˢf൬ਔႭj¨ᐖ
ߤ
ٙவ၇
ڢ
ɓ
ߧ
݊௰˴
ࠅ
ٙღᖟd̴
ڜ
ᖟɛ
ࡁ
ҬՑ০࿁
ᐖसٙᔊᐕ
ج
f©
ॲ
ߒ
̹
MemorialSloan-Kettering
ᐖसʕːٙ˴͙ጒ
(HaroldVarmus)
ɰᗎΝவɓᝈᓃf͙ጒΪ೯ତୋ
ɓ၇
ߧ
ᐖਿΪϾʱԮə
1976
ϋٙፕԎဧᔼኪᆤd˼
ٙӺϓ
މ؈
ਿΪᜊମኬ
ߧ
ᐖसٙଣሞఢ֛ਿᓾf
˼ίд؍ִ݁ಂග̈ሊ͛Ӻ৫৫
ڗ
d
ᔖಂගᐖसӺ൬ɽషᄣ
ڗ
f˼Ⴍj¨வ݊ɓଡ଼
੬ڢ
ᗭ༆ٙਪᕚfҢ
ࡁ
Ϋ᎘ᐼ݊ᙂࣛග
ܘ
f
30
ϋගdɛᗳ˷࿁ᐖसϓΪΌ್ೌٝՑጐଢ଼ə
ɽඎٝᗆf©
研究戰果喜憂參半
1971
ϋdࣛٙ
ߕ
ᐼ୕̵дؒί
ߧ
ึٙઋ
ے
˖ʕϣ͍ό̈¨
ߕ
ɛᔼ
ط
வ၇༈ϥٙशष
ٙࣛዚϓᆞədҢ
ࡁ
Ꮠ༈ණʕ྅Ӻࣨᜊ˸ʿ
೮˜ଢ
ה
˹̈ٙɢඎɓᅵԸਂவԫfᜫҢ
ࡁ
ٙ
ɛ͏ே
މ
ྼତவ
ࡈ
ͦᅺϾኧ৸©fΝϋ
12
˜d̵д
ؒᖦᐖस
ج
ࣩd܁бྼ݄ᐖसБਗ
ࠇ
ྌf༈ධ
ج
ࣩٙࣨːlz࢙݊ᓒɽᐖसӺ
ה
NCI
ٙᅼeᔖபձᇍఖd֛༈Ӻ
ה
ٙ
ڗה
͟ᐼ୕dϾ
ڢ
ͭੰӺ৫
NIH
նdഗʚ
ᐖसӺ
ה
˸࿁ٙዹͭdΝࣛɽɽᄣ̋ə࿁
ᐖसӺ൬ٙ˕౪dᐖसӺ
ה
ٙ൬˷
ίɓցʘගɪပ
23%
d༺Ց
2.3
ᄂʩdІԟࣛ˸Ը
ܵᚃᖂʺdӊϋ൴
50
ᄂ
ߕ
ʩdуԴ
ڐ
ϋԸஷጱദ
ʥϞᄣೌಯfІ
1971
ϋ˸ԸdͭᐖसӺ
ה
ʊ
ίᐖस߅ኪӺeᐖस
ط
ᐕձཫԣ˙ࠦ͆༟
900
ᄂ
ߕ
ʩf
ኋ၍ɛᗳΝᐖसٙҤፅʊϞɮჃٙዝ̦dШ݊˸
ͭ
ج
ٙҖόdҳɝམ༟ԸਂவԫdϾ˲݊߅ኪ
ྼɢ௰੶ٙԸપਗdவίֻ݅ٙɛᗳ˖̦ɪ
ԨʔεԈdவɰ݊
1971
ϋ
ߕ
ஷཀٙᐖस
ج
ࣩίɛ
ᗳҤᐖ̦ɪՈϞࠠ
ࠅ
จ່ٙࡡΪf
Ш̻݊ːϾሞdኋ၍
ߕ
Іɪ˰
ߏ
90
ϋ˾˸Ըᐼٙ
ᐖस೯षଟձϥɳଟேίᇠ࿔ɨࠥd
7
၇˴
ࠅ
ᐖसٙ
ϥɳଟɰʊϞᜑٙɨࠥdШᐼϾԊdவఙҤᐖ
ʘԨ͊՟ཫซٙϓ̌dɛ
ࡁ
Ӻ൳εe൳ଉ
ɝd೯ତଘҰՑٙਪᕚ൳εd̋ɪӺϓ
؈
Ցᑗ
ґᏐ͜ᒔϞ
ڗܘ
ɓ
ࠅ༩ݬ
ԐdΪϤఖᔎவఙၾᐖʘ
̰ٙʘ
ن
ɓٜӚϞ৾ࢹཀf
1986
ϋd͛
ي
୕
ࠇ
ኪ
ߒ
ጫgܰਔίอ
ߵ
ࣸᚆᔼኪᕏႦɪ೯˖
̈d
15
ϋԸᐖसٙ೯͛ଟձϥɳଟਿ͉ɪӚϞʡჿ
ᜊʷd
ߕ
͍ί̰̘வఙ০࿁ᐖसٙ
ن
d͟Ϥˏ
೯əܵᚃεϋٙ
ن
ሞf
2003
ϋdաɛᗳਿΪଡ଼
ࠇ
ྌ
ҁϓ
ܝ
ٙᆀᝈઋၫᅂᚤdᐖसӺ
ڗהה
τᅃ
ኁgඹgࡾ
ٵ
ˋႺண֛əɓ
ࡈ
ͦᅺd၈
2015
ϋϞ
ૐഐҼᐖस੭Ըٙ೨߮ձϥɳfவɓண֛ͦᅺˏৎ
əһɽ
ن
ᙄfΪ
০މ
࿁ᐖसٙ
ࠇ
ྌᒱ್ʊ࣐હəɽ
ඎٙ͛նdШ݊ϞԬᐖसdνঈ໗ᐖe໘ᐖeӿᐖ
ഃԨӚϞҷഛf
2009
ϋ
8
˜dฌᅃശg͚ɗ
ࠔ
ਞᙄࡰϥెग़
ᇭሯᆯ{{ɓ၇ᗭ˸
ط
ᓹٙ໘໕ᆯdவΎϣՐዧə
ߕ
ձყٟึᗫ
ء
ె໕ᆯ࿁ɛᗳ͛ն̶ٙɽ
۾
উfͦ
ۃ
ස
ߕ
ɓϋఱ
ࠅ
อᄣ
150
ຬᐖसઃ٫dԨӊ
ϋྮԐ
50
ຬɛٙ͛նdࢨʔε̬ʱʘɓٙɛ
௰ࡁ
ேึΪ໕ᆯϾϥɳfԸІʕ௰ɽ̹۬ɪऎٙ௰อ
1,2,3,4,5,6,7
9,10,11,12,13,14,15,16,17,18,...84