保健 - 第56期 - page 25

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CAN
YOU LIVETO
sO()YEARS?
At a
recent
conference
of the
World
Future Society,
Prof
M
Zey
ol
Montclair State
University
and
Prof
Donald
B
Louria,
of
the
University
of
Medicine
& Dentistry of
New Jersey, believed longevity
was
realistic.
Major diseases are controlled; as
are
some of
the
defects accompanying aging
can
promote diseases.
Moreover, work
on
reversing or halting
the
aging process may also contribute substantially. Work
on
under-
standing genes/gene mutations that prolonged
life
are accomplished
in
fruit flies, earthworms and
rodents.
A
life span
of
500 years had ever been claimed by some specialists but
others
refuted
these
as "science
fiction". Dramatic extension
of
the
life
span would depend on altering the onset
of
disabilities that accompany
the aging process
by
changing the genetic
makeup.
Telomeres that cap the chromosomes, are related to
cell
longevity and are regulated
by
an enzyme
telomerase.
The feeding of 4-phenybutyrate
(PBA)
to fruit flies
increases lifespan
-
the delay
in
aging may result from the altered
physiologicalstate.
ln studies involving the
octopus, a "death hormone" was documented; on
the other hand,
PBA may be the "elixir
of
immortality" as
sought
by
past
emperors.
A
University of
the
Ryukyus
study found Okinawan centenarians had
macroph-
ages that
were
more competent
than others
in engulfing foreign
"invaders".
There
is
thus
a lot of work
to
be
done
on
longevity but
the
outlook seems optimistic.
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