H!AEg
EFHR
Chen Yu-Min
IMMUNE
FUNCTION OF
THE
THYMUS
The development
of
the capactity
to
respond to an
immunogen
is
depend-
ent on
a
functioning thymus gland
as
well as on other lymphoepithelial struc-
tures. The fetal
thymus gland
behind
the
sternal bone
is
now known essential
for
the development
of
competent cell-me-
diated immunity, as
it
most
likely
serves
to
mature stem
cells
into
competent T
lymphocytes;
if
it is lacking or abnor-
mal, partial or complete deficiency
in
cellular
immunity occur. Cell-mediated
immunity
is
important
in
protection
against viral, fungal, and protozoan in-
fections, as well as against malignancy
and automimmune disease.
ln
addition,
T cells
appear
to
be necessary for
normal antibody production
by
B
lymphocytes. Thus,
a
functioning intact
thymus
is
essential and
crucial for the
normal immune defense function
of
the
body.
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