ਖ਼ᕚઞ॰
59
̈dԪஐͣe
ڥ
ऄა࿁ཫԣˇЄसՈϞࠠ
ࠅ
ᄆ
࠽
fɓԬӺᜑͪdɹऄਿაd˴
ࠅ
Ϟ˕ᗡऄਿ
აdԋऄ㺸ᶶഃdतй݊
ڥ
ऄა
(leucine)
dΪ̴̙ஷ
ཀዧ
ݺ
mTOR
ɓ၇ஐͣዧ㺛ձ
eIF
ᔕᙇৎΪ
ɿࢰ
ڮ
ආஐͣሯΥϓfՉΥϓঐɢˢՉ̴ऄਿ
ა
ߒ৷ࠅ
10
࠴
fϤ̮dᒔ̙ҵՓஐͣሯٙʱ༆f
ɷ
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ᗭ൯ϼԸᆰdவ̩༑݊ϼϋ೯၅Ⴍ
ج
̤ٙɓ၌fԫྼɪdϼϋɛ˄
אߛ
˄ᆰேʔ݊
၅fतй݊ԟ၇ʔٙᆰԒd࿁ϼϋɛՉϞf
੬੬̙˸Ցdϼɛᜊᆰʘ
ܝ
d߉್ɓ㰦षԷν
ف٬
ɨԸఱۭəfவ݊Ϊ
މ
शषձ
ڗ
ಂ
ٶ
ґˇ
ਗdԴЄЂ
ݴ
̰ϾࠠಯჀdϾࠠၾᐄቮً
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ί
ݔ
ɓ
ܓ
ɪd˾
ڌ
əɛ࿁शषٙ
ת
Ҥঐɢfᐄቮ
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ޥ
ɢЭɨ݊৷
ܓ
ᗫٙf
ቇᙧቇඎٙ༶ਗ
࿁ɓ໊༶ਗٙ৷Κषɛdʔ݊ʔ
ࠅ
༶ਗədϾ݊̀
ࠅ
Ϟतࣿٙ༶ਗᅼόd˼
ࡁ
ც
ࠅ
ٙ݊ཀྌண
ࠇ
ٙeቇᙧeቇඎeܵʘ˸
ܩ
ٙ༶ਗf
ܛ
ٙ˴ਗ
ό༶ਗdν੭ः༶ਗձҤ
ڜ
༶ਗѩ̙ᄣ̋ЄЂஐͣ
ձጟࡡٙᎷ௪d̋৶ᎥЄٙА૰ృᐑၾ˾ᑽdᄣ
̋৶ᎥЄ
ߗ
ɢܸٙ݊ЄЂίၪܵϗᐵࣛ
ה
ঐܵᚃ
͜ɢٙࣛග
א
ˀልϣᅰeЄЂሯeඎ੶
ܓ
e
ݓ
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ܓ
fу
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ᙧࣛd༶ਗɓᅵ̙˸ʺ͛
ݺ
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Бਗঐɢdಯˇൻ
ࡀ
ၾ̰ঐdᜑഹಯˇːА၍शष
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Ϟ༸݊dɛϼၺϼdவ༑̙ʔfϼɛٙจ
̮ෆdৰə˂Өeԓ၆ഃdഒɽεᅰ݊ൻ
ࡀ
fତ
ί࿁ϼɛٙᚐଣɪd੬੬
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əʔᜫ˼
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षɛεሽഹdˇԐਗfШՉ
؈ܝ
̙ঐఱϤɓ
ٶ
ʔ
ৎd
؈ܝ
ఘlԸd࿁ϼɛБਗঐɢٙʺd
݊εჿٙࠠ
ࠅ
f
ਖ਼ٙ
ܔ
ᙄ
2013
ϋ
6
˜d͟ʕᐄቮኪึ˴፬ٙʕϼᙧʷ
ၾੰ৷ࢤሞእίɪऎ̜කfίᗫ
ء
ϼϋˇЄ
सٙሞእɪdਖ਼
ࡁ
ఱνОਂλ৶ᎥЄٙ
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d
ཫԣˇЄसٙ೯͛d̈ə˸ɨ
ܔ
ᙄf
ɓe
ڭ
ᗇɧ
ࠅ
ϞቇඎஐͣሯdӺᜑͪdӊ˚ஐ
ͣሯʱৣ̻ፅdঐϞࣖዧ೯৶ᎥЄٙ͛
ڗ
ᆑ
ɢdబўᎴሯஐͣሯٙ
ي
ϞᆰЂᗳeЂe
̲Ⴁۜഃf
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ቇඎ̂ၪ͛९
D
d൳Ը൳εٙӺᜑͪ̂
ၪ͛९
D
ՈϞҷഛϼϋ৶ᎥЄሯඎձ̌ঐٙЪ
͜f
ɧe
ಯˇ᎑࿒͛
ݺ
˙όdਂՑঐ१ʔѬdঐԐʔ
१dΥଣආБᒦf
̬e
ڭ
൛Υቇٙঐඎᙲɝf
Skeletal Muscle & Health
Sarcopenia is the loss of skeletal (voluntary) muscle mass up to 30% with “grip index <30 in males, <20 in females; a walking speed
of <0.8 m/sec. Sarcopenia results from senility, deficiencies of protein and energy diets or inflammatory diseases, organ damage,
prolonged bed-ridden state, inadequate or no exercises, etc. The mechanism is complex: could be related to increased “tumor
necrosis factor”, interleukin-6, leptin, myostatin and decreased adiponectin, interleukin-15: all subject to further research. Prolonged
bed rest without exercises leads to loss of muscle mass and weight loss: to some extent, linked to immunity. Aerobic and resistance
exercises increase muscle protein and glycogen reserve; enhance circulation and metabolism of skeletal muscles: enhance endurance
for sustained contraction and repetitive actions; improve their quality, intensity and softness. Exercises help the elderly regain self-
mobility, reduce falls and death rates of cardiovascular diseases. A sedentary life is your worst enemy: never confine to bed in order
to avoid falls! Take adequate protein, energy and vitamin D; avoid prolonged sitting: if you can stand, don’t sit; if you can walk, don’t
stand!