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Dr-
Ghui Shiu-Hon
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The
liver is of
vital importance
in
the
metabolism
of
carbohydrate, fat,
protein, hormone and bilirubin, and
in
the detoxification and elimination
of
toxic substances.
Damage to
the
liver
may
or
may not obviously affect its ac-
tivity
since the liver has considerable
functional
reserve.
However,
several
biochemical tests directly or indirectly
related
to
liver
function are
routinely
performed as
a
panel
or
profile
of
liver
function
tests.
These include alanine
transaminase, aspartate transaminase,
alkaline phosphatase, gamma-glutamyl
transpeptidase, bilirubin, total protein
and
albumin. The
results of these bio-
chemical
tests are frequently
non-
specific,
since
they
reflect
the
basic
pathological processes common
to
many
conditions.
On the other
hand,
tests
of
liver
lunction
alone are
often
insensitive indicators of liver
disease.
Therefore, it
is
important to
be
aware
of the limitations of such biochemical
tests,
the
results
of
which should be
in-
terpreted together with clinical informa-
tion
and
findings
of
other techniques
lor
the diagnosis and management of liver
disease.
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