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Xu Guan-Jian
HEREDITY
OF NEOPLASM:
CANCER FAMILY
AND FAMILIAR CANCER
While
numerous
studies
documented genetic factors
play
a role
in
many common types
of
tumors,
strong
and direct support
of genetic
susceptibility to
cancer,
1.e.,
neoplasm
inherited
lollowing
Mender's Role
is
relatively
rare.
ln general, the interplay
of
a
number of factors is responsible
for
the development of malignant dis-
ease.
lt has been shown
that
more
than
90% of patients
with
neoplasm
are
re-
lated to
the
interplay of environmental
and genetic
factors.
However,
for
a
number
of
many
other
malignancies
such as bladder carcinoma, gastric
car
cinoma, breast cancer in males, liver
carcinoma, acute myeloblastic
and
chronic lymphocytic
leukemia,
Hodgikin's disease, and etc., the
he-
reditary pattern
is
well defined and the
frequency
in
family members is
high.
This phenomenon can
be
explained by
both environmental and genetic effects
on tumor development.
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