14
癌病探索
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免疫策略展雄風
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ٙ¨࢙Ⴖ©
The Mystery of Viruses Killing Cancer Cells
Viruses were first found to kill cancer cells with the anecdotal Italian patient with advanced uterine cervix cancer with a documented
cure in 1912: by a rabies vaccine. Emily Whitehead, 6, had a relapsed leukemia (ALL) with no options except an investigational
immunotherapy at the University of Pennsylvania implemented through modifying her T-lymphocytes with modified HIV virus and
re-injected to her: extremely violent reaction ensued but strangely survived. Subsequent patients also did well but all these may well
exhaust the global supply of gamma globulins required for the rest of their lives. In 2001, UK scientists found an attenuated herpes
virus kills malignant melanoma cells; in 2003, US scientists found genetically modified adeno-viruses kills brain cancer cells. Stacy
Erholtz had a relapsed malignancy of the bone marrow plasma cells (MM) despite enduring all the chemotherapy and 2 stem cell
transplants. At the Mayo Clinic, an investigational measles viral vaccine (10 million times the usual vaccination dose) induced a violent
reaction, high fever of 40.6oC. Yet, she recovered completely. Despite such violent reactions, the prospects are tremendous…
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Ըࢮʷष
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f
2005
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11
˜dɓ
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ҷிϾԸٙ๓ᆯष
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H101
ཀʕ
ۜᖹ္ۜຖ၍ଣ҅
SFDA
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