保健 - 第94期 - page 56

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ա᜗࿴ۨҷᜊdᕎɿஷ༸ක׳dNa+ lz ݴ ҖϓਗЪ
ཥЗdЄᜄၪϗᐵf͟׵ઃ٫᜗lz̈ତəɓ၇˜Ҥ
n-Ach ա᜗ٙҤ᜗ ™d̴̙ʍᓔAchၾ Achա᜗ٙഐ
Υdא ݊̋஺Achա᜗ٙlzчၾॎᕸd੽ϾᅂᚤəЄ
Ђ͍ٙ੬ϗᐵdߧԴषɛዑ७Єݺ ਗೌɢ
ա᜗ၾеޥˀᏐ
Tollᅵա᜗(Toll-like receptor,TLR)݊ոϞеޥ ٙࠠ
ࠅ ա᜗fе ޥ ˀᏐ̙ʱ މ ոϞе ޥ ձቇᏐ׌еޥ Շ
၇fίոϞе ޥ ʕd୚ߤ νОᗆй̮Ըٙڢ ʉҤ
ࡡk୚ ߤ ӚϞ଻ຒd̴࿁Ҥࡡٙᗆйd၌፠୚ߤ ٙ
ա᜗f1996 ϋdί؈ᖼʕ೯ତəToll ਿΪٙ༺ڌ ପي
ίҤช ݑ ཀ೻ʕৎࠠ ࠅ ٙЪ͜fՇϋܝ dɦίʃཽ
ʕᆽႩTollਿΪପي ա᜗͍݊୚ഽ၇ݔഐ࿴ϓʱٙա
᜗fTLR ί΢၇еޥ୚ ߤdν̶አ୚ߤeዓ߉ً୚ߤ
ഃѩϞ༺ڌהfɛᗳʕʉ೯ତəЇˇ11၇ TLRd΢І
ᗆйʔΝٙҤࡡdԷνTLR1̙ᗆй୚ഽe੔͛ᔥf
ILR3̙ᗆйषݭ ഃfTLR ࿁ҤࡡᗆйeഐΥܝdу̙
䥊ਗ ڦ໮ᔷኬd䥊ਗɓҭࠠ ࠅٙਿΪd(ν فڮ सਿ
Ϊ )ʿ Iۨʍᓔ९ഃd˸ʿˏৎ୚ߤ ٙ ݺʷd੽Ͼ׳ɽ
࿁षࡡ᜗ٙ૨ෆ׌f
ա᜗ၾชݑ׌शष
ա᜗ίɽεᅰช ݑ ׌शषٙ೯षɪϞഹࠠ ࠅ ٙᗫ
ڷ f୚ഽeष ݭ eࡡᔥഃषࡡ᜗ ࠅช ݑ ੖˴୚ ߤ d
࠯΋ࠅ ᘬɓ၇˜ᓂ९ڝ ™࿁୚ߤ ٙतମա᜗ٙഐΥձ
ᗆйfה ˸d̥ϞўϞ༈षषࡡ᜗ٙա᜗ʑึ೯षd
щ ۆ ఱʔึ˿ɛ೯षfԷνdͣఓ૖ഽߧࠅषdఱ
ࠅቦ̴ٙ९ݭၾɛ᜗୚ߤᇫɪٙͣఓ ९ݭա᜗ഐΥd
ίա᜗ʧኬٙlzчЪ͜ɨආɝߤ lz᜗dί ߤ lz᜗ٙ
ა׌ᐑྤɨdͣఓ ೯९ݭ ͛ᜊ࿴d੽Ͼˏৎ୚ߤ ٙ
षଣᜊʷfɦνdᎍ඾ֹഽᘬഹᎍ඾९ݭၾɛʃ໑
ᓂᇫ୚ ߤ ɪٙतମ׌ա᜗ഐΥdʔ̙৕ዧݺ ᇫɪٙ
໗㹷ᐑʷ㺛d͛ϓcAMPdԴߤ ᆉʕٙcAMPўඎɽ
ᄣdኬ ߧ ʃ໑ɪͤ୚ ߤ ᇫஐͣ࿴ۨҷᜊdɽඎಣᕎ
ɿձ˥ʱɿܵᚃᔷ༶ɝ໑ഢdˏৎᘌࠠٙ໖ᓧձ୭
˥f
ΪϤdᏐ͜ᓂ ९ڝҤ᜗א ա᜗ᗳЧ ي d̙ڜ ᓙᓂڝ
९ၾա᜗ٙഐΥdɦא ண ج Դᓂ९ڝ ʱ༆dԴषࡡ
᜗̰̘ߧ षɢdே̙༺Ցԣطෂ ݑषٙͦٙf
ա᜗ष
Ϊա᜗ٙᅰඎeഐ࿴ א ሜື̌ঐᜊʷdԴʘʔঐʧ
ኬৣ᜗ίཪ୚ߤʕᏐϞٙࣖᏐה ˏৎٙशष၈މ˜ա
᜗ष ™fա᜗ମ੬̙˸ ڌତ މա᜗ɨሜ אಯઽd٫ۃ
ܸ݊ա᜗ᅰඎಯˇd ٫ܝܸཪ୚ ߤ ࿁ৣ᜗Րዧٙˀ
Ꮠ׌ಯࢮ א ऊ̰fա᜗ମ੬͵̙ ڌ ତ މ ա᜗ɪሜ א
ᄣઽdԴཪ୚ ߤ ࿁ৣ᜗ٙՐዧˀᏐཀ ܓ dɚ٫ѩ̙
ኬ ߧ ୚ ڦߤ໮ᔷኬღᖟdආϾᅂᚤशषٙ೯͛ձ೯
࢝f
ա᜗ष̙ʱ ፲މෂ׌ա᜗षeІԒе ޥ ׌ա᜗षe
ᘱ೯׌ա᜗षɧᗳf፲ෂ׌ա᜗ष݊͟׵ᇜᇁա᜗
ٙਿΪ߉ᜊdԴա᜗ॹ̰eಯˇ א ഐ࿴ମ੬ˏৎi
ІԒе ޥ ׌ա᜗ष݊Ϊ᜗lzପ͛Ҥ᜗ٙІԒҤ᜗ኬ
ߧ d̙ژՐዧ׌Ҥ᜗ ™ˏৎ୚ߤ࿁ৣ᜗ٙˀᏐ׌ᄣ
੶dא ژڜ ᓙ׌Ҥ᜗ ™ʍᓔৣ᜗ၾա᜗ٙഐΥdኬ
ߧ ୚ ߤ ٙˀᏐ׌ࠥЭiᘱ೯׌ա᜗ମ੬ܸ݊ԟԬΪ
ίशषཀ೻ʕ̈ତٙᜊʷf༊ᑘՇ ࡈ ա᜗षٙԷɿ
Ⴍ׼νɨf
࢕ૄ׌৷ᑔոቐАस
˜࢕ૄ׌৷ᑔոቐАस ™݊ɓ၇፲ෂ׌ա᜗षfబў
ᑔոቐٙЭ੗ ܓইஐͣ(LDL)ա᜗݊ɓ၇ᄿع πί׵
୚ ߤᇫɪٙա᜗d̴݊ɓ၇ጟஐͣfঐၾLDL ᒶ୐޴
ഐΥdԨ຾ա᜗ٙʧኬආɝ୚ ߤd LDLί๓㺛᜗lzࠥ
༆Ԩᙑ׳̈ᑔոቐdԶഗ୚ ߤ ˾ᑽც ࠅ dԨࠥЭА
ᆉᑔոቐٙўඎfઃ٫͟׵ਿΪ߉ᜊˏৎLDL ա᜗ᅰ
ඎٙಯˇ א ̌ঐମ੬dመνա᜗ၾৣ᜗ٙഐΥঐɢ
ࠥЭeա᜗ٙlzчॹ௘eա᜗ٙΥϓաฦ א ୚ ߤ lz
ᔷ༶ღᖟഃd˸ߧ࿁૶ৰLDLঐɢࠥЭf݂̈͛ܝd
LDL ўඎу৷׵͍੬d̙༺͍੬ɛٙᅰ࠴ dԨ˲೯͛
ਗএഎᅵ೷ʷٙࠬᎈɰ׼ᜑᄣ̋f
ࠠसЄೌɢ
ࠠसЄೌɢ݊ɓ၇ग़຾-ЄЂගෂኬ̌ঐღᖟٙІԒ
е ޥ षfڌ ତ މ աଢ଼ٙዑ७Є೹ԫ ݺ ਗуชೌɢd
Ⴠ٫සଢ଼ʿ଻Єdࠠ٫̙ ت ʿΌԒЄЂd ޟ ЇΪխ
іЄաଢ଼ϾΚʿ͛նf
ί͍੬ઋ ر ɨd຅ग़຾ላਗ ༺ת༶ਗग़຾͋૓ࣛd
ग़຾͋૓ึᙑ׳̈ɓ၇̣ɔ。ᑔ᜽(Ach) ٙي ሯd̴
̙˸ձ৶ᎥЄɪٙ˜๧᜽ۨɔ。ᑔ᜽ա᜗ ™ഐΥdԴ
預防勝於治療