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A
BRIEF
DISCUSSION
ABOUT
PARKINSON'S DISEASE
This condition, which
is
also
called paralysis agitans, was first iden-
tified
and
classically described
by a Brit-
ish doctor James Parkinson
in
1817.
Typically,
this
is a disorder of middle
aged person or seen in late life, with
very
gradual progression and
a
pro-
longed
course.
Despite
the
general
medical familiarity with the condition
and an
eltensive
literature on the sub-
iect, it can
not
yet
be said
that
the
pathologic changes
or
paralysis agitans
are fully
understood.
Recent biochemi-
cal studies
have shown
that there
is a
decrease of dopamine level
in
the cau-
date nucleus and putamen, two impor-
lant
neuronal
tissues taking care
of
many forms of movement of
man.
ln
its
lully
develop form, this disorder can
not be mistaken for any other cerebral
diseases.
The stooped posture, the
stitfness and slowness of movement,
the fixity
of
facial
expressions
and
the
rhythmictremorof
the
limbs,
which sub-
sides on an actively willed movement
or complete relaxation, are familiar to
every clinician.
Although
lhere is
no effective
treatment
that
is known
to
halt
or
re-
verse the neuronal degeneration that
presumably
underlies
Parkinson's dis-
ease, methods are now available which
can bring about
a
considerable degree
of
relief from symptoms
in
many
pa-
tients.
Along with general supportive
measures including
a
well planned pro-
gram
ol
exercise, activity
and
rest, ex-
pert
physical
therapy and
emotional
support, patients generally require a
carefully
thought out
program of
treat-
ment specially aimed at counteracting
the pathologic disorder that
produces
their
disabilities.
This can
be medical
(with
drugs
like L-dopa
and
its
deriva-
tives) or surgical, or a combination of
both, and frequent and regular medical
consultations with doctors should
be
encouraged.
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56