保健 - 第77期 - page 11

9
शषԣط
དྷ՞ֲঢ়϶Ꭶէංר ͂ࠌ Ꭶᖞؿ؝ᏻʿ࣐e௖ٶ τȹ
ඖޢӠͳढ़Ƀ700ԝདྷ՞ֲঢ়϶Ꭶ੩ّcၤξɐר͂ࠌ
Ꭶᖞޚˈcէංר ᖞ϶Ꭶ੡ԷઁԹّᄈ˱1ࠛe
ࣛԕطᐕٙࠥᏀอᖹ
Ϭ 1996α޻ਝ FDA ғ࠿଱ȹ࠯ঢ়϶Ꭶࣂӻ؝ᏻณᖞ
COREVe r apami l ႇቸ€˞Ԟcɺᒾτณᖞਐ˖e
2003α޻ਝFDAғ࠿ؿ ΔဍଥԿDiltiazem€ࣂӻ ࠌᎦ
؝ᏻณᖞCardizem LA. Εયɐ10ࣂ רᖞ܃cԯГወ۹
ᘷי Εᐽ઱2 ࣂcɐʟ10ࣂϭɻʟ༠ঢ়ࢋc ܛᙩ 24ɩ
ࣂeȹඖޢ Ӡྦྷ429 ԝঢ়϶Ꭶ੩ّဣרک ͂Cardizem
LA. ԯ ࠌᎦࢋࠤΕξ઱6ࣂϭɻʟcྦྷէං϶Ꭶᄧᚊɺ
ɣcॶτࢽઁԹ઱ࢋ϶Ꭶe
ЎܰԎڈ ֺτঢ়϶Ꭶ੩
ّяᎶઔ͂ࣂӻࠌᎦ؝
ᏻe̋τྦྷڈҭ ؿێঢ়
϶Ꭶ͉મdէං϶Ꭶ
ܛ ᙩᄈঢ়€˞ʥτ઱ࢋ
ঢ়϶Ꭶ੩ّ˿ϣᄬፕ
͂eΕࣂӻ؝ᏻ౨ංᎶ
ց౨А৽ྸ϶Ꭶဟಡc
ԎᎶΕᔢ࢑ ܞ ኒɎ͂
ᖞc˞Лէං϶Ꭶࠌ੡
༦ГϤೕ́ʶd຾dഋ
˚߬ኂւؿ ॠ϶e
CHRONOTHERAPY FOR HYPERTENSION: NOT TO BE IGNORED
According to the Framingham studies in the US, only 48% of hypertensives are well controlled. Failure to control could indicate
that the hypertension is secondary to sleep apnoea, chronic kidney diseases, kidney artery narrowing, diabetes, adrenal tumours,
etc.; for others, "chronotherapy" principles may help as blood pressure has a circadian rhythm with a "morning surge" and an
evening low - the "dipper" type; the "morning surge" may be an independent risk factor for the more frequent sudden death and
acute coronaries in the early morning. For the "non-dipper" type (without evening low) there would be problems with a single
dose of antihypertensive drugs taken in the morning. Moreover, for theses patients, hypotension during the night would not be
a problem. Thus, the "non-dipper" type should take "calcium channel blockers" in the evenings to be more effective; beta-
blockers are better taken during the day; diuretics, before retiring. Resistant hypertensives are mostly of the "non-dipper" type,
Cardizem LA tablets are extended release tablets containing diltiazem, a "calcium-channel blocker"; when taken at 10 pm, may
well work better. Consult your doctor!
ࠠ ࠅ ஷ ѓ
ڐ௰͉̊ᇜ։ึ̜කᓒɽึᙄdމጐ฽ᓋᏐಯˇરލeືߒ͜ॷٙᐑڭ݁ഄdʿ
Դቡᛘᇍఖ౷ʿΌଢd˸೯౨͉̊һɽࣖूf݂࿁ڭ਄ᕏႦ‘ʘе൬೯ݼdܼ̍਷lz
е൬ඉ੔ഃ˙όdЪ̈Ꮸীձሜ዆fӔ֛੽ 2010ϋ3˜΅dୋ78ಂ€݆֙໮ක֐dҷ͟
˸ၣɪوе൬೯׳މ˴f
խᝫɓΣฌᚐձᗫː ͉̊ʘ਷lz׀༐ᛘ٫dሗɪၣٜટ೮ɝ͉ึၣ१j
€http://www.healthcarehk.orgᓭᚎeቡᛘfאගટஷཀɪၣඩډ€http://www.yahoo.come
ԋဂ€http://www.google.comeϵܓ€http://www.baidu.comഃၣ१dฤర˜࠰ ಥڭ਄
՘ึ™e˜ڭ਄ᕏႦ™ᓭᚎf
Ҏૐɽ࢕࿁͉̊ʘอણ݄dഗʚሓ༆ձᘱᚃɽɢ˕ܵމ޸f න཰
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࠰ ಥ ڭ ਄՘ึ ᔫ઼
ɚཧཧɘϋɤɚ˜ʞ˚