Hl+l@'
H}la*€)hd
3Ffr
troa+fr*e)
Zhang
Yu
Can
"Bird
influenza"
transmit
from
person
to
person?
Chicken flu
may
wipe
out
chicken
flocks;
the
H5N1
virus
requires an en-
zyme found only
in
the gut of birds but
not
in
the human lung. But,
the
1st hu-
man
infection of
HSN1
virus
had al-
ready
occurred
in
a Hong Kong
kid
in
1997.
Without any immunity, any
hu-
man-to-human
spread
is
truly
disastrous.
ln
1970, with a favorable
"room temperature"
of 410C,
the gut
of
the
Ukaine duck was found
to
be har-
boring
the
chicken
flu virus.
With
mutation,
it
is now more aggressive,
but,
to
achieve
human-to-human
transmission, the
avian
flu virus
must
overcome the human immune system;
survive well at a much lower
"room
temperature" of 33-34"C of the
respi-
ratory system; adhere elfectively
to
human cells and copy itself repeatedly
inside these cells. With receptors
for
both human and avian
flu
viruses
in
the
respiratory passages, the pig
is a
very
convenient
"mixing
vessel" for
human
and avian
flu
viruses to combine
to
enable human-to-human transmission!
ln China, the common practice of mix-
ing of
ducks and chickens provides a
convenient
"transit'for
the chicken flu.
2 categories of drugs are available
for
treatment: amantadine
/
remantadine
and zanamivir
/
oseltamivir - with dif-
ferent side effects.
Fortunately,
China
has
now achieved a
vaccine
lor
the
high pathogenicity
H5N1
virus;
in
Vietnam,
the code
ol
the
H5N1
has
also been broken
and
the
results of a
rapid
blood
test for
avian
flu
is
now
available
within
12 hours.
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