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Ying Jie-Mo
PROGRESS
IN GENE
THERAPY
Genes are fragments of the DNA
and
they
control
growth, development
and
diseases.
From the 50s, research
on genes have been developing very
rapidly.
Gene
therapy
is
the
most im-
portant breakthrough
in
the control of
many
diseases.
Certain genetic mate-
rial
are inserted
into
the body cells and
its
full expression would bring
about
the
most "radical" treatment for cerlain
diseases.
Gene
transfer
is
the
key
to
all
gene
therapy
methodology.
ln
the
past, only single gene delects can
be
"repaired",
nowadays,
even
multiple
gene defects can
be
tackled.
Even the
scope of gene therapy
is
progressively
widening
-
in
addition
to
treating inborn
genetic
errors,
cancers,
heart
and blood
vessel, nervous system, autoimmune
(immunity against
own
tissues)
and
even
infective
diseases
like AIDS or
hepatitis can
also
be
tackled.
Current
methods of gene
introduction
involves
insertion of the genes into the cells
taken
out of the
body and
then
reinlused
back.
Gene insertion can be
done
through viral, physical
or
chemi-
cal
methods.
Despite some initial
success, gene therapy
is
still "rudimen-
tart''
but by 2025, most investigational
work on
gene therapy should
be
completed.
4
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