15
疾病防治
ҢٙΚᎈ൙Пlz࢙ʕ৷АᏀЦ༰ɽᛆࠠf߰ୌΥ
ɨΐૢʘɓ٫ʔცܲɪ
ڌ
൙ПϾᏐٜટΐ
މ
ːА
၍ष৷Κɛ໊j
1
Э
ܓ
ইஐͣᑔոቐ
⩾
4.9mmol/l
190mg/dl
i
2
1.8mmol/l
70mg/dl
⩽
Э
ܓ
ইஐ
ͣᑔոቐÖ
4.9mmol/l
190mg/dl
d˲ϋᙧί
40
๋˸
ɪٙጟ҇षઃ٫f
10
ϋːА၍ष೯ष̻ٙѩΚᎈܲÖ
5%
ЭΚe
5%
{
9%
ʕΚձ
⩾
10%
৷ΚʱॴfҢ
ܸ
ی
ܲΚᎈٙഃॴd֛ίᏐ͜˼͓
ܝ
Э
ܓ
ইஐͣᑔոቐٙཪͦᅺʱй֛
މ
Э
/
ʕΚÖ
3.4mmol/l
130mg/dl
e৷ΚÖ
2.6mmol/l
100mg/dl
f
ίːА၍षɓॴཫԣʕdЭ
ܓ
ইஐͣٙ˥̻Ԩʔ
ც
ࠅ
ࠥ˄ЭfᏐ͜˼͓ᗳᖹ
ي
̙ঐϞЄЂʔԄ
ˀᏐձӿᛔᗫฦෆfϞɓධӺᒔ೯ତ৷੶
ܓ
ٙ
˼͓Ꮠ͜
ܝ
d̙ᜑഹᄣ̋อ೯ጟ҇षٙࠬᎈdɰ
ၾϼϋɛႩٝ̌ঐెʷϞᗫf
USPSTF
ٙӻ୕ʱؓ൙
ПԨ͊ᜑͪʔΝ੶
ܓ
ٙ˼͓ίːА၍षɓॴཫԣ
ʕٙЪ͜ϞОࢨମfɦᛡɓॴཫԣʕ˼͓ٙᏐ
͜
މ
ࣛ༰
ڗ
dΪϾ
މ
ᒒеʔԄˀᏐd
ܔ
ᙄ
ࠅ
Ӌίɓ
ॴཫԣʕᏐ͜Э{ʕഃኒඎ˼͓dᒒеᏐ͜ɽኒ
ඎ৷੶
ܓ
˼͓d˸ഄτΌf
˰
ޢ
10
ϋːА၍षٙࠬᎈ൙Пʕ̙˸̈d
ᎇഹϋᙧᄣ
ڗ
ࠬᎈɰᄣɽf್Ͼ
USPSTF
މ
Оਗ਼ϋᙧ
֛ί
40
{
75
๋ճfவ݊Ϊ
މ
࿁
≥76
๋ٙ֠͊̋͜˼
͓ٙϼɛॹ˶˼͓ɓॴཫԣᐏू{ࠬᎈˢٙӺ
༟ࣘd݂ʔЪપᑥf
อ
ڐ
͍ίක࢝ɓධ
STAREE
Ӻd݊০࿁ೌːА၍
ष˲ೌጟ҇षeϋᙧ
≥70
๋ٙϼɛᏐ͜˼͓ၾτᅌ
ኒٙˢ༰d˸ϥɳ
+
ᖝь
+
ಞღආ࢝ʿ˴
ࠅ
ʔԄːА
၍ԫːЄϥ
+
໘ʕ
+
ːА၍ϥɳЪ
މ
ᝈ࿀ٙ
ᓃܸᅺdཫ
ࠇ
ί
2020
ϋʮбӺഐ
؈
f֣ࣛdҢ
ࡁ
ಂ
ܙ
76
๋˸ɪːА၍षٙʕe৷Κɛ໊ɰঐ˼
͓ɓॴཫԣʕᐏूf
How to Use Statins for Best Prevention of Cardio-vascular Diseases?
Statins are very commonly employed for managing hyperlipidemia (high blood cholesterol and/or high low-density lipoprotein
cholesterol (LDL-C) and/or low high-density lipoprotein cholesterol (HDL-C), eg, by reducing LDL-C to <40 mg/dl, the reduction of
risks of fatal cardio-vascular disease (CVD) and non-fatal coronaries were reduced by 11% at 1 year and 36% at 6 years but there
are significant side effects of statins, especially when taken for very prolonged periods. According to the recommendations of the
US Preventive Services Task Force (USPSTF), adults aged 40 to 75 years with no history of CVD (ie, symptomatic coronary artery
disease or ischemic stroke) and 1 or more CVD risk factors (dyslipidemia [LDL-C >/=130 mg/dl or HDL-C </=40 mg/dl], diabetes,
hypertension or smoking), and a calculated 10-year CVD event risk >/=10%, it is recommended that they use a low- to moderate-
dose statin for the prevention of CVD events and mortality. On the other hand, for adults 76 years and older with no history of CVD, the
USPSTF concludes that the current evidence is insufficient to assess the balance of benefits and harms of initiating statin use for the
primary prevention of CVD events and mortality. Thus, the use of statins is not just based on the cholesterol level!
