保健 - 第80期 - page 76

76
Why do Newborns have Brain Haemorrhage: Deficiency of Vitamin K-dependent Clotting Factors
Although neck rigidity usually signifies meningitis, it could also signify brain haemorrhage. A 47-day old patient had deep coma, anaemia, bulging
of the anterior frontanelle (sign of raised intra-cranial pressure) and bleeding tendency. Another 2-month old baby had purplish-red, watery stool,
bleeding tendency, anaemia, bulging of the anterior frontanelle and neck rigidity. Both had deranged clotting profiles, signifying deficiency of vitamin
K-dependent clotting factors. Vitamin K acts as an enzyme in the liver when synthesizing clotting factors II, VII, IX and X; lack of vitamin K means
poor clotting. Vitamin K is found in greens, fruits, beans and animal liver, etc.; the gut’s beneficial bacteria also synthesize vitamin K but human milk
has little vitamin K; prolonged antibiotics kill beneficial bacteria; prolonged diarrhea leads to poor absorption of vitamin K; liver dysfunction prevents
synthesis of vitamin K. Prevention is to give the occasional cow’s milk even for breast fed babies; paediatricians advocate routine vitamin K to all
newborns. Nursing mothers should take more greens, fruits and beans; avoid prolonged broad-spectrum antibiotics.
綜合報導
診斷與治療
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