54
名醫專訪
Biological Therapy: a New Weapon to Combat Tumors: Interviewing Prof Liu Wah: Chief,
Biological Therapy Research Laboratory, Zhong Shan Hospital, Fudan University
2 methods of immunity enhancement are feasible: “active immunity” is to enhance the body's own immunity mechanisms; “passive
immunity” is to deliver some already-enhanced cells by injection into the body: an "adoptive immunity". Similarly, the current strategy
of immunotherapy against cancer cells is also based on the adoptive principle, e.g., cytokine-induced killer (CIK) cells that were
obtained from the cancer patients (peripheral blood) themselves (the autologous mode), would be processed in novel in vitro 3-D
models of tumor biology: a much more appropriate environment (than the 2-D ones) to process cells. Lymphocytes from the patient's
blood are incubated with anti-CD3 monoclonal antibodies, interleukin (IL)-2, IL-1, and interferon gamma (IFN-gamma). When injected
intravenously back to the patient, CIK cells recognize and kill tumor cells of minimal residual cancers. "Safety first" is mandatory
for such hi-tech infusion methods, as introducing contaminated substances into the body is disastrous. Nevertheless, with due care
and concern and attention to details, the prospects of such immunotherapy against cancer has good future prospects and should be
implemented more widely, albeit more research are also required.
̙݅˸Ъ
މ
˓ஔe׳ʷᐕٙႾп
ط
ᐕ˓
ݬ
dɰ
̙˸ఊዹԴ͜Ъ
މ
˴
طࠅ
ᐕ˓
ݬ
flz໕ᆯ˴
ࠅ
˸Շ၇Җόπίdɓ၇Җό݊ྼ໕ᆯd̤
ɓ၇݊ฆʃٙᔷष㵿fҢ
ࡁ
̙˸л͜၇ʔ
Νٙ҅
ط
ᐕٙϞࣖ˓
ݬ
dν˓ஔe࢛᎖eТ
ီɠe൴ᑊɠഃ࿁ྼ໕ᆯආБጐٙ
ط
ᐕf
ΝࣛආБ͛
طي
ᐕԸછՓίٙ
א
ಞवٙ໕
ᆯ
ߤ
d
໕މ
ᆯषɛԶΌ˙Зٙ
ط
ᐕfҢ
ࡁ
̙˸ίவ
ࡈ
˙Σ
ן
࢝Չᑗґྼ͜ᄆ
࠽
f˸е
ޥ
ط
ᐕΝ၇ʔΝٙՉ˼
ط
ᐕ˙
ج
ԸԶ
ࡈ
ʷٙ
ط
ᐕd˸ʿᑌΥ၇ʔΝٙе
ޥ
ᐕ
ج
Ը
ط
ᐕᐖᘣfҢ
ࡁ
ڦ
˸е
طޥ
ᐕ
މ
ਿᓾٙ໕ᆯ
ط
劉華教授簡歷
ᐕٙอഄଫਗ਼Ϟпҷഛ໕ᆯઃ٫ၝΥ
ط
ᐕٙ
ࣖ
؈
ձಯჀ
ݭ
ਓЪ͜fе
طޥ
ᐕΝཪΣᖹ
طي
ᐕɓᅵd࿁ʔˇె໕ᆯٙ
ط
ᐕேᐏəᆽ
ʲٙᐕࣖfཪΣձе
طޥ
ᐕٙᑌΥᏐ̙͜ঐ˾
ڌ
əె໕ᆯ
ط
ᐕٙอ˙Σjᐕࣖᆽʲe
ݭ
ਓ
Ъ͜Ⴠeԣ˟໕ᆯూ೯ձᔷeʔ࢙ପ͛
ߗ
ᖹ˸ʿ৷໕ᆯઃ٫ІԒٙе
ޥ
̌ঐf
࠽
̈ٙ݊d˸
ݭߤ
T
ˋ
ߤ
TCL
މ
ਿᓾٙҤ໕ᆯе
طޥ
ᐕdᒔ̙˸͜ʦ
ܝ
Ӻ
ක೯˸մఖ
א
ʕ̯ۨাኳ
މߤ
˴ٙ໕ᆯཫԣ
ߴޥ
fν
؈
ঐਂՑཫԣ໕ᆯٙ೯͛d
ۆ
ॆ
͍จ່ɪ܁ѓjɛᗳ௷əె໕ᆯl
ତూ͇ɽኪʕʆ
ᔼ৫໕ᆯ͛
طي
ᐕ
Ӻ܃˴e܄ࢭ
બdࠠɽอᖹ
௴Ⴁ߅Ҧࠠɽਖ਼ධ
ਖ਼dੵϪ͛
ي
ᔼᖹ
ყΥЪྷʷ̻ၽਖ਼
dɪऎ̹Ўಿषਖ਼
ے
༔։ࡰึ։ࡰf
1982
ϋίɪऎᔼ߅ɽ
ኪ
᙮ڝ
ʕʆᔼ৫ᐏ၂ɻ
ܝ
dίϡೌᗭeಷ
১બܸኬɨԫऊʷӻ୕໕ᆯٙᑗґ
ᔼኪe͛
ي
ኪձе
ޥ
ኪӺf
1986~1987
ϋ
ߕࠌ
ॲ
ߒ
ψͭɽኪආБϞᗫ໕ᆯٙ௹
ɻ
ܝ
Ӻfʘ
ܝ
ί
ߕ
Г
ی
ᔼኪʕːд
ᔜψᘽࣸᚆᕿतՅഁᔼ৫
ܝ
Ӻ
ࡰe৷ॴӺࡰʿ
ߤ
ձ͛
ي
ʷኪྼ᜕܃
˴f
2005~2012
ϋίɪऎ
ږ
ᔼ৫ණྠ
Бਜʕːᔼ৫
ߤ
Ӻ܃৷ॴӺ
ࡰձ˴d
ࠋ
பԨҁϓ໕ᆯɧၪ͛
ي
ᅼۨ
ٙ௴
ܔ
˸ʿ೯əɓ၇Ⴁ௪อɓ˾໕ᆯ
ޥ
ߴ
ٙอ฿ׂձอ˙
ج
f
2007
ϋৎdίɪऎ
ూ͇ɽኪʕʆᔼ৫໕ᆯ͛
طي
ᐕӺ܃ዄ
˴ձ܄ࢭબdᘱᚃආБ໕ᆯ
ߤ
е
طޥ
ᐕ˙ࠦٙӺf