保健 - 第94期 - page 56
56
աۨҷᜊdᕎɿஷ༸ක׳d
Na+
lz
ݴ
ҖϓਗЪ
ཥЗdЄᜄၪϗᐵf͟ઃ٫lz̈ତəɓ၇Ҥ
n-Ach
աٙҤd̴̙ʍᓔ
Ach
ၾ
Ach
աٙഐΥd
א
݊̋
Ach
աٙlzчၾॎᕸdϾᅂᚤəЄЂٙ
͍੬ϗᐵd
ߧ
Դषɛዑ७Є
ݺ
ਗೌɢ
աၾе
ޥ
ˀᏐ
Toll
ᅵա
(Toll-like receptor,TLR)
݊ոϞе
ޥ
ٙࠠ
ࠅ
աfе
ޥ
ˀᏐ̙ʱ
މ
ոϞе
ޥ
ձቇᏐе
ޥ
Շ
၇fίոϞе
ޥ
ʕd
ߤ
νОᗆй̮Ըٙ
ڢ
ʉҤ
ࡡk
ߤ
ӚϞຒd̴࿁Ҥࡡٙᗆйd၌፠
ߤ
ٙ
աf
1996
ϋdί
؈
ᖼʕ೯ତə
Toll
ਿΪٙ
༺ڌ
ପ
ي
ίҤช
ݑ
ཀʕৎࠠ
ࠅ
ٙЪ͜fՇϋ
ܝ
dɦίʃཽ
ʕᆽႩ
Toll
ਿΪପ
ي
ա͍݊ഽ
၇ݔ
ഐϓʱٙա
f
TLR
ί၇е
ޥ
ߤ
dν̶አ
ߤ
eዓ߉ً
ߤ
ഃѩϞ
༺ڌה
fɛᗳʕʉ೯ତəЇˇ
11
၇
TLR
dІ
ᗆйʔΝٙҤࡡdԷν
TLR1
̙ᗆйഽe͛ᔥf
ILR3
̙ᗆйष
ݭ
ഃf
TLR
࿁ҤࡡᗆйeഐΥ
ܝ
dу̙
䥊ਗ
ڦ
ᔷኬd䥊ਗɓҭࠠ
ࠅ
ٙਿΪd
(
ν
فڮ
सਿ
Ϊ
)
ʿ
I
ۨʍᓔ९ഃd˸ʿˏৎ
ߤ
ٙ
ݺ
ʷdϾ׳ɽ
࿁षࡡٙ૨ෆf
աၾช
ݑ
शष
աίɽεᅰช
ݑ
शषٙ೯षɪϞഹࠠ
ࠅ
ٙᗫ
ڷ
fഽeष
ݭ
eࡡᔥഃषࡡ
ࠅ
ช
ݑ
˴
ߤ
d
ࠅ
ᘬɓ၇ᓂ
९ڝ
࿁
ߤ
ٙतମաٙഐΥձ
ᗆйf
ה
˸d̥ϞўϞ༈षषࡡٙաʑึ೯षd
щ
ۆ
ఱʔึ˿ɛ೯षfԷνdͣఓഽ
ߧࠅ
षdఱ
ࠅ
ቦ̴ٙ
९ݭ
ၾɛ
ߤ
ᇫɪٙͣఓ
९ݭ
աഐΥd
ίաʧኬٙlzчЪ͜ɨආɝ
ߤ
lzdί
ߤ
lzٙ
აᐑྤɨdͣఓ
೯९ݭ
͛ᜊdϾˏৎ
ߤ
ٙ
षଣᜊʷfɦνdᎍֹഽᘬഹᎍ
९ݭ
ၾɛʃ໑
ᓂᇫ
ߤ
ɪٙतମաഐΥdʔ̙ዧ
ݺ
ᇫɪٙ
໗㹷ᐑʷ㺛d͛ϓ
cAMP
dԴ
ߤ
ᆉʕٙ
cAMP
ўඎɽ
ᄣdኬ
ߧ
ʃ໑ɪͤ
ߤ
ᇫஐͣۨҷᜊdɽඎಣᕎ
ɿձ˥ʱɿܵᚃᔷ༶ɝ໑ഢdˏৎᘌࠠٙ໖ᓧձ୭
˥f
ΪϤdᏐ͜ᓂ
९ڝ
Ҥ
א
աᗳЧ
ي
d̙
ڜ
ᓙᓂ
ڝ
९ၾաٙഐΥdɦ
א
ண
ج
Դᓂ
९ڝ
ʱ༆dԴषࡡ
̰̘
ߧ
षɢdே̙༺Ցԣ
ط
ෂ
ݑ
षٙͦٙf
աष
Ϊաٙᅰඎeഐ
א
ሜື̌ঐᜊʷdԴʘʔঐʧ
ኬৣίཪ
ߤ
ʕᏐϞٙࣖᏐ
ה
ˏৎٙशष၈
މ
ա
ष fաମ੬̙˸
ڌ
ତ
މ
աɨሜ
א
ಯઽd
٫ۃ
ܸ݊աᅰඎಯˇd
٫ܝ
ܸཪ
ߤ
࿁ৣՐዧٙˀ
Ꮠಯࢮ
א
ऊ̰fաମ੬͵̙
ڌ
ତ
މ
աɪሜ
א
ᄣઽdԴཪ
ߤ
࿁ৣٙՐዧˀᏐཀ
ܓ
dɚ٫ѩ̙
ኬ
ߧ
ڦߤ
ᔷኬღᖟdආϾᅂᚤशषٙ೯͛ձ೯
࢝f
աष̙ʱ
፲މ
ෂաषeІԒе
ޥ
աषe
ᘱ೯աषɧᗳf፲ෂաष݊͟ᇜᇁա
ٙਿΪ߉ᜊdԴաॹ̰eಯˇ
א
ഐମ੬ˏৎi
ІԒе
ޥ
աष݊Ϊlzପ͛ҤٙІԒҤኬ
ߧ
d̙ΪՐዧҤ ˏৎ
ߤ
࿁ৣٙˀᏐᄣ
੶d
א
Ϊ
ڜ
ᓙҤ ʍᓔৣၾաٙഐΥdኬ
ߧ
ߤ
ٙˀᏐࠥЭiᘱ೯աମ੬ܸ݊ԟԬΪ
ίशषཀʕ̈ତٙᜊʷf༊ᑘՇ
ࡈ
աषٙԷɿ
Ⴍνɨf
ૄ৷ᑔոቐАस
ૄ৷ᑔոቐАस ݊ɓ၇፲ෂաषfబў
ᑔոቐٙЭ
ܓ
ইஐͣ
(LDL)
ա݊ɓ၇ᄿ
ع
πί
ߤ
ᇫɪٙաd̴݊ɓ၇ጟஐͣfঐၾ
LDL
ᒶ
ഐΥdԨաٙʧኬආɝ
ߤ
d
LDL
ί๓㺛lzࠥ
༆Ԩᙑ׳̈ᑔոቐdԶഗ
ߤ
˾ᑽც
ࠅ
dԨࠥЭА
ᆉᑔոቐٙўඎfઃ٫͟ਿΪ߉ᜊˏৎ
LDL
աᅰ
ඎٙಯˇ
א
̌ঐମ੬dመνաၾৣٙഐΥঐɢ
ࠥЭeաٙlzчॹeաٙΥϓաฦ
א
ߤ
lz
ᔷ༶ღᖟഃd˸
ߧ
࿁ৰ
LDL
ঐɢࠥЭf݂̈͛
ܝ
d
LDL
ўඎу৷͍੬d̙༺͍੬ɛٙᅰ
࠴
dԨ˲೯͛
ਗএഎᅵʷٙࠬᎈɰᜑᄣ̋f
ࠠसЄೌɢ
ࠠसЄೌɢ݊ɓ၇ग़
-
ЄЂගෂኬ̌ঐღᖟٙІԒ
е
ޥ
षf
ڌ
ତ
މ
աଢ଼ٙዑ७Єԫ
ݺ
ਗуชೌɢd
Ⴠ٫සଢ଼ʿЄdࠠ٫̙
ت
ʿΌԒЄЂd
ޟ
ЇΪխ
іЄաଢ଼ϾΚʿ͛նf
ί͍੬ઋ
ر
ɨdग़ላਗ
༺ת
༶ਗग़͋ࣛd
ग़͋ึᙑ׳̈ɓ၇̣ɔ。ᑔ
(Ach)
ٙ
ي
ሯd̴
̙˸ձ৶ᎥЄɪٙۨɔ。ᑔա ഐΥdԴ
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